Yes, on an animal head, the flow will be better with the plug shimmed up, but it'll hurt the performance on the dyno from my experience (on stockers.) There's some good argument for wanting a hotter plug for the already over-rich plate engines, and it'll show up on an A/F meter, but I still end up back on the same old 3910X plug at the end of the day. Something you may want to experiment with is a slight change in ignition timing. Having that plug and extra .080" in the combustion chamber may not seem like much, and at the speed of the flame kernel when ignited it may be immeasurable, but it is something to consider. A slight movement of the coil will change the timing considerably. I've made an adjustment opening the coil air gap additionally and found that to help with the 3910X plug.
For sure, there's no one way to build an engine to make solid power. From J-remey's post above -- 4 different builders' engines in one pit. I bet they all run fine, but all are built slightly different. My guess is that one is a favorite of the driver whether it makes the most power on the dyno or not.