Things that blew head gaskets. Any combination that got the head too hot.
Put a big guy in an Animal, put sticky tires on it, tape up the blower housing, set the kart up too tight, put it on a tight sprint track with lots of slow turns or one with a hill to pull up, put too much timing in it would also help.
Heaven forbid you would run it on gas.
In a short time you could replace the head gasket. Maybe even the head if it was warped bad enough.
I still have a 2 X 6 X 6 steel plate that i used to straighten them with. Problem was it usually didn't stay straight for very long.
Taking the tape off the blower housing was worth .2 to .3 hp but who would ever want to do that???