E85 is transported in the same tankers with the same equipment as Gasoline. It "can" be more corrosive if left sitting for a while, but only because it's Hygroscopic. Ethanol of it's self unlike Methanol, isn't corrosive at all. It's the water that it easily absorbs that makes it more corrosive. Methanol is considered a weak acid, but so is water. Since Methanol is also hygroscopic, with water it's not a pretty picture. Ethanol is not an acid or base, but when combined with water becomes acidic. Which tends to happen when it sits because it's hygroscopic. Hopefully that clarifies it a little better.
The benefits are almost identical to Methanol, slightly less downsides. Nascar uses like 15% Ethanol in their fuel, Indy I think is now fully E85. So if it's available easily, and cheap.... Why not? Jetting will not be the same as either, so you'll have to account for that. But, if you flush it like we do methanol just to be safe you'll be more than fine. But, the benefits are there.